Everything after Ace's death was mix of vengeance and cutting his losses. Pretty comparable to Yamamoto's, where Seireitei and Ichigo somewhat mirror extended crew and Luffy.. One of the most heartbreaking moments in Bleach: Thousand-Year Blood War takes place when Yhwach defeats and kills Captain-Commander Genryūsai Shigekuni Yamamoto. After the battle, Yhwach.
Genryusai Yamamoto is one of the strongest characters in Bleach, but his death is so shockingly underwhelming on so many levels. Bleach has seen characters come and go, but these losses and deaths were some of the hardest for anime fans to handle.