Specific Effects on NSAIDs The reduced stomach size with all types of gastric surgery presents a major problem with the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Administration of NSAIDs in these patients carries an increased risk for serious damage to the stomach pouch, which may result in gastric ulcers.. This recommendation was primarily aimed at preventing complications of NSAID use in gastric bypass patients and was eventually adopted to include patients undergoing sleeve gastrectomy (SG) [3, 4]. The effects of NSAID use on SG patients have not been adequately studied to determine a best-use practice.
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However, NSAIDs are not safe for managing pain after gastric bypass. You should avoid taking any non-steroidal anti-inflammatory (NSAID) drugs unless your physician tells you otherwise.. Background: Laparoscopic Roux-en-Y gastric bypass (LRYGB) surgery is a safe and effective procedure for patients with severe obesity. One potential complication of LRYGB is the development of marginal ulcers (MUs). Nonsteroidal anti-inflammatory drugs (NSAIDs) are known to significantly increase the likelihood of developing marginal ulcers after surgery. However, the risk associated with low.